Shortages, substitutes and uncertainty: the new reality of drugs supplies

Yaroslav Astakhov/Shutterstock.com The reliable supply of drugs is fundamental to any healthcare system, yet shortages remain a persistent problem. Disruptions arise from a range of causes: manufacturing failures, fluctuating demand, regulatory changes and wars. Around 60% of drug shortages are linked to manufacturing bottlenecks, while insufficient reserves of both finished products and raw ingredients continue […]

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Nobel prize awarded for discovery of immune system’s ‘security guards’

Three scientists have been awarded the 2025 Nobel prize in physiology or medicine for discovering how the body stops its own immune system from turning against itself. Shimon Sakaguchi from Osaka University in Japan, Mary E. Brunkow from the Institute for System Biology and Fred Ramsdell from Sonoma Biotherapeutics, both in the USA, identified specialised […]

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