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GENEVA, 12 September 2025 — The World Health Organization (WHO) has reported a sharp rise in global cholera deaths for the second consecutive year, with fatalities increasing by 50% in 2024 compared to 2023. Over 6,000 people died from the disease last year, despite cholera being both preventable and treatable.
Cholera cases rose by 5%, with outbreaks reported in 60 countries—up from 45 the previous year. Africa, the Middle East, and Asia accounted for 98% of all cases. Twelve countries reported more than 10,000 cases each, including seven experiencing major outbreaks for the first time. Comoros saw a resurgence after 15 years without reported cases.
The case fatality rate in Africa climbed from 1.4% to 1.9%, exposing critical gaps in healthcare delivery and access to treatment. Notably, one-quarter of deaths occurred outside health facilities, underscoring the need for stronger community-based interventions.
WHO attributes the rise to conflict, climate change, displacement, and inadequate water and sanitation infrastructure. The organization continues to respond with emergency medical supplies, surveillance support, and community engagement.
A new oral cholera vaccine, Euvichol-S®, was added to the global stockpile in early 2024, helping maintain emergency reserves. However, demand far exceeded supply, prompting continued use of a single-dose regimen. In 2024, 40 million doses were approved for use across 16 countries.
With 31 countries already reporting outbreaks in 2025, WHO maintains its assessment of global cholera risk as very high and urges sustained investment in prevention, treatment, and vaccine production.
